SyntenyVista

Visualization of genome comparisons is an important research tool in biology, medicine and agricultural research. We present a new visualization system, SyntenyVista, which allows for interactive exploration of genome comparisons. It incorporates a novel feature called cartoon scaling designed to improve the user's ability to understand gene relationships. SyntenyVista is being deployed in the context of e-Science where it will provide an entry point to integrated data on genomes, animal models of disease, and disease genes

A physiological measure of shifting connections in the Rana pipiens retinotectal system

The retinotectal connections of developing Rana tadpoles and froglets have been studied using light-pipe techniques to directly assay the pattern of the projection from the retina to the tectum. The projection site of the retina surrounding the optic nerve head was determined at two different stages of development (late larval and metamorphic frog) on the same animal. Small electrolytic marker lesions were used to mark the tectal sites to which the optic nerve head projected at these two times. Comparison of the positions of the two lesions gives a direct measure of the shift in the projection during the interlesion time interval of one week. The results indicate a shift in the projection of 275 µm week–1 in late larval life. Previous work in Xenopus using the light-pipe techniques indicated a qualitatively similar shift during equivalent stages of development, but significantly smaller in magnitude. In the present study, topographic postsynaptic units could be recorded at all stages investigated, indicating functional synapses between the optic nerve fibres and the tectum. Thus, these studies offer evidence of a significant shift in the functional connection pattern of the amphibian retinotectal map during development, in agreement with the recent anatomical data from other laboratories on the Rana and goldfish visual system

Elastic-plastic finite-element analyses of thermally cycled double-edge wedge specimens

Elastic-plastic stress-strain analyses were performed for double-edge wedge specimens subjected to thermal cycling in fluidized beds at 316 and 1088 C. Four cases involving different nickel-base alloys (IN 100, Mar M-200, NASA TAZ-8A, and Rene 80) were analyzed by using the MARC nonlinear, finite element computer program. Elastic solutions from MARC showed good agreement with previously reported solutions obtained by using the NASTRAN and ISO3DQ computer programs. Equivalent total strain ranges at the critical locations calculated by elastic analyses agreed within 3 percent with those calculated from elastic-plastic analyses. The elastic analyses always resulted in compressive mean stresses at the critical locations. However, elastic-plastic analyses showed tensile mean stresses for two of the four alloys and an increase in the compressive mean stress for the highest plastic strain case

Materials constitutive models for nonlinear analysis of thermally cycled structures

Effects of inelastic materials models on computed stress-strain solutions for thermally loaded structures were studied by performing nonlinear (elastoplastic creep) and elastic structural analyses on a prismatic, double edge wedge specimen of IN 100 alloy that was subjected to thermal cycling in fluidized beds. Four incremental plasticity creep models (isotropic, kinematic, combined isotropic kinematic, and combined plus transient creep) were exercised for the problem by using the MARC nonlinear, finite element computer program. Maximum total strain ranges computed from the elastic and nonlinear analyses agreed within 5 percent. Mean cyclic stresses, inelastic strain ranges, and inelastic work were significantly affected by the choice of inelastic constitutive model. The computing time per cycle for the nonlinear analyses was more than five times that required for the elastic analysis

VisGenome: visualization of single and comparative genome representations

VisGenome visualizes single and comparative representations for the rat, the mouse and the human chromosomes at different levels of detail. The tool offers smooth zooming and panning which is more flexible than seen in other browsers. It presents information available in Ensembl for single chromosomes, as well as homologies (orthologue predictions including ortholog one2one, apparent ortholog one2one, ortholog many2many) for any two chromosomes from different species. The application can query supporting data from Ensembl by invoking a link in a browser

The performance of decentralized school systems : evidence from Fe y Alegría in Venezuela

This program evaluation estimates the effects on standardized test scores of graduating from the Fe y Alegría private school system in Venezuela. The authors find an Average Treatment Effect on the order of 0.1 standard deviations (approximately 16 percent of the average score), using a control group of public school students. These effects are significantly larger for households at the bottom of the distribution, and smaller for those at the top. The authors posit that the better performance of the Fe y Alegría system stems from their labor contract flexibility and decentralized administrative structure.Tertiary Education,Education For All,Secondary Education,Primary Education,Teaching and Learning

Math anxiety, intrusive thoughts and performance: Exploring the relationship between mathematics anxiety and performance: The role of intrusive thoughts

The current study examined the relationship between math anxiety and arithmetic performance by focusing on intrusive thoughts experienced during problem solving. Participants (N = 122) performed two-digit addition problems on a verification task. Math anxiety significantly predicted response time and error rate. Further, the extent to which intrusive thoughts impeded calculation mediated the relationship between math anxiety and per cent of errors on problems involving a carry operation. Moreover, results indicated that participants experienced a range of intrusive thoughts and these were related to significantly higher levels of math anxiety. The findings lend support to a deficient inhibition account of the math anxiety-to-performance relationship and highlight the importance of considering intrusive thoughts in future work

Attitudes and Family Farm Business Performance

This study aimed to identify the top performing and the bottom performing family farm businesses based upon business performance, and then compare and contrast the perceptions and attitudes towards acquiring management skills and attributes that lead to improved business performance. Using extensive interviews data were obtained from 200 family farm businesses from New South Wales and Victoria covering a range of enterprises. The key findings were, firstly, that for all farmers the maintaining of a stable family relationship was of paramount importance in the running of the farm business. Secondly, that the Top 20% of farmers had high levels of self-efficacy and thus possessed the capability and the competence to perform tasks successfully. High performers also were more committed to the creation of long-term wealth and viewed business skills as a higher priority for training. Low performers were more highly committed to the farm's environmental health, placed a greater emphasis on production and sustainability for training and were more likely to give a lower priority to business issues. Both groups agreed that formal training that involved practical farmers with education skills providing them with tailor-made modules were best suited to their personal learning needs. The consistently high priority of family and business issues suggests that the opportunity exists to integrate the training of attitudes and skills with family, sustainable business practices and community issues. The study was funded by the Rural Industries Research and Development Corporation.Farm Management,